Best Physiotherapy in Barnsley since 2004

HCPC & CSP registered Free parking on site
New patient? Register online Patient reviews
Call to book01226 391201 Book online
Call to book01226 391201

REGENERATIVE MEDICINE IN BARNSLEY

Medical ozone therapy, the science explained

Medical ozone uses a precise mix of oxygen and ozone to help the body calm inflammation and repair damaged tissue. At Physio Barnsley it is given by certified medical ozone clinicians and combined with advanced physiotherapy, for results that last.

Over 1400 Active Clients

Book a complimentary suitability call Or call us01226 391201
Oxygen molecules splitting in an electrical field and re-forming as ozone (O3) inside a medical ozone generator. Caption: Conceptual visualisation of ozone generation using an electrical discharge.
Since 2004Physiotherapy and medical ozone

What is medical ozone?

Ozone (O3) is oxygen with an extra atom. That extra atom makes it highly reactive, and in small, controlled doses the body responds to it by switching on its own defences against inflammation and damage.

Medical ozone is made on demand from pure medical oxygen, at concentrations measured to the microgram. It is never breathed in. It is given by injection or mixed with a small amount of your own blood.

  • Over 100 years of medical useOzone was used to disinfect wounds during the First World War, and has been refined in clinics across Europe ever since.
  • Tested in clinical trialsRandomised controlled trials have tested ozone injections for back pain, knee osteoarthritis, shoulder and heel pain.
  • Given by certified cliniciansPeter and Craig Hartley are HCPC registered physiotherapists, certified medical ozone clinicians and trained phlebotomists.

Why oxygen matters for healing

Every injury heals in three overlapping phases. Each one depends on a good supply of oxygen, and long-standing pain often means tissue has become stuck, inflamed and short of it.

  1. Phase 1

    Inflammation

    The body cleans up the damage. Useful at first, but when it doesn't switch off it causes ongoing pain and stiffness.

  2. Phase 2

    Repair

    New tissue and blood vessels form. This is the phase that most needs oxygen and blood flow.

  3. Phase 3

    Remodelling

    New tissue strengthens and lines up with the load it carries. Rehab exercise guides this phase.

Where ozone comes in

A controlled dose of ozone acts as a short, mild stress signal. The body answers by turning up its antioxidant and anti-inflammatory defences and improving local blood flow and oxygen delivery. The aim is to move stuck tissue out of inflammation and back into repair, while physiotherapy guides the remodelling.

Two ways we use medical ozone

Targeted

Prolozone: ozone injections

Injected directly into or around a painful joint, tendon, ligament or muscle. Backed by clinical trials for back pain, knee osteoarthritis, shoulder and heel pain.

How ozone injections work → Whole body

IV ozone autohaemotherapy

A small amount of your own blood is mixed with medical ozone and returned through a drip, delivered to a strict medical protocol.

How IV ozone works →

What the research shows

The strongest evidence for medical ozone is for injections into painful joints, tendons and the back.

61%

of patients with disc-related back pain were pain-free six months after ozone injections, compared with 33% after a dummy treatment.1

16 trials

A 2026 review of 1,172 patients found ozone injections reduced knee pain and improved movement compared with placebo.2

Steroid-free

In head-to-head trials for shoulder and heel pain, ozone injections matched steroid injections at three months.34

Ozone with advanced physiotherapy

Ozone calms the pain and inflammation. Physiotherapy fixes the movement, strength and loading problems that caused them. Together, they give you the best chance of a lasting result.

  • Assessed by a physiotherapistWe find the cause of your pain before deciding if ozone will help.
  • Hands-on treatment and rehabManual therapy, exercise and, where useful, shockwave, traction or Cybex.
  • Progress reviewed every visitSo your plan changes as you improve.

Ozone results, in our patients' words

Read all reviews →
Arthritis in both feet · Craig Hartley
“I’ve been in pain for 8 years!! … I’ve just finished my last session with Craig, after 48 hours I got out of bed expecting the same as usual (pain), I was walking normal, no pain.”
David Evans · Google review, posted by Margaret Evans
Knees · Craig Hartley
“I have just completed a course of Ozone Therapy. I can now walk without pain, the stiffness has eased and I’m looking forward to a more mobile life in the future without surgery.”
Barbara Rooker · Google review
Back and neck · Peter Hartley
“In October I started a course of the Ozone therapy treatment for back pain and neck issues, I am really pleased with the results of my back treatment from which I’m now pain free.”
Julie Westlake · Google review

Medical ozone questions

Anything else? Call us on 01226 391201 or book your complimentary suitability call.

What is medical ozone therapy?

Medical ozone therapy uses a precise mix of medical oxygen and ozone, given by injection or mixed with a small amount of your own blood, to help the body calm inflammation and repair tissue.

Is it the same as ozone in the air?

No. Ozone should never be breathed in. Medical ozone is made from pure medical oxygen at measured concentrations and is only given by injection or through your own blood.

Is medical ozone safe?

Research reviews report no serious side effects from ozone injections, and minor reactions are uncommon. IV ozone follows a strict protocol, including a full health check before your first session.

Which ozone treatment is right for me?

For a painful joint, tendon, ligament or the back, it is usually ozone injections. We'll talk you through the options on your complimentary suitability call.

Who gives the treatment?

Peter Hartley and Craig Hartley, HCPC registered physiotherapists, certified medical ozone clinicians and trained phlebotomists.

Find out if ozone is right for you

Answer a few short questions, then choose a time for a complimentary 30 minute call with one of our physiotherapists.

Book a complimentary suitability call

Existing ozone patients: Prolozone or Autohemotherapy

References

  1. Paoloni M, et al. Intramuscular oxygen-ozone therapy in the treatment of acute back pain with lumbar disc herniation: a multicenter, randomized, double-blind, clinical trial of active and simulated lumbar paravertebral injection. Spine. 2009;34(13):1337–44. View study
  2. Chen F, et al. Ozone injection for knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials. Frontiers in Pain Research. 2026. View study
  3. Atar MÖ, et al. Comparison of ultrasound-guided subacromial corticosteroid and ozone (O2-O3) injections in the treatment of chronic rotator cuff tendinopathy: a randomized clinical trial. Korean Journal of Pain. 2023;36(1):128–36. View study
  4. Bahrami MH, et al. Local ozone (O2-O3) versus corticosteroid injection efficacy in plantar fasciitis treatment: a double-blinded RCT. Journal of Pain Research. 2019;12:2251–9. View study

Results vary from person to person. Your physiotherapist will advise whether ozone is suitable for you.